Effect of Genetic Polymorphism on Capecitabine-Induced Toxicity in Egyptian Cancer Patients
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
The goal of this observational study is to study the effect of a single nucleotide polymorphism in the CES1 gene (rs2244613) on capecitabine-induced toxicity in Egyptian cancer patients. This study will help in understanding the interindividual variability in the CES1 gene and the effect of a single nucleotide polymorphism in this gene (rs2244613) on capecitabine-induced toxicity in participants already taking capecitabine-based chemotherapy as part of their regular medical care.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients with breast or colorectal cancer receiving capecitabine-based chemotherapy
• Age \> 18 years
• ECOG PS 0-2.
Locations
Other Locations
Egypt
Department of Clinical Oncology, Faculty of Medicine, Menoufia University
RECRUITING
Shibīn Al Kawm
Contact Information
Primary
Raghad Nassar, Teaching Assistant
raghad.essam22@pharma.asu.edu.eg
01004446077
Time Frame
Start Date: 2024-04-01
Estimated Completion Date: 2025-08
Participants
Target number of participants: 80
Related Therapeutic Areas
Sponsors
Collaborators: Menoufia University
Leads: Ain Shams University